Rare Cyclophosphamide-Induced Hemorrhagic Cystitis in a Chinese Population with Rheumatic Diseases

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Rare Cyclophosphamide-Induced Hemorrhagic Cystitis in a Chinese Population with Rheumatic Diseases

OBJECTIVE The aim of this study was to investigate the prevalence, severity, risk factors, and treatment outcomes of cyclophosphamide (CYC)-induced hemorrhagic cystitis (HC) in patients with rheumatic diseases. METHODS We collected the clinical data from 1284 consecutive patients admitted to The First Affiliated Hospital of Sun Yat-Sen University who were treated with CYC between 2006 and 201...

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Effect of Lycopene on Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats

Background: Cylophosphamide is used alone or in combination with other drugs for treatment of neoplastic diseases. Hemorrhagic cystitis is a major potential toxicity and dose limiting side effect of cyclophosphamide. The aim of this study was to evaluate the effects of lycopene compared with some antioxidants for the prevention of cyclophosphamide induced hemorrhagic cystitis in rats. Methods: ...

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Incidence of cyclophosphamide-induced hemorrhagic cystitis in Chinese Han population with autoimmune disease

Cyclophosphamide (CTX), has been widely used for treating various human malignancies as well as autoimmune disease. Although CTX could rapidly decrease the response of immune system, it also could result in severe adverse effects, such as hemorrhagic cystitis (HC). In this study, we investigated the occurrence of HC in patients taking CTX from Chinese Han population and divided all cases into d...

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effect of lycopene on cyclophosphamide-induced hemorrhagic cystitis in rats

background: cylophosphamide is used alone or in combination with other drugs for treatment of neoplastic diseases. hemorrhagic cystitis is a major potential toxicity and dose limiting side effect of cyclophosphamide. the aim of this study was to evaluate the effects of lycopene compared with some antioxidants for the prevention of cyclophosphamide induced hemorrhagic cystitis in rats.   methods...

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Effect of Lycopene on Cyclophosphamide- Induced Hemorrhagic Cystitis in Rats

Background: Cylophosphamide is used alone or in combination with other drugs for treatment of neoplastic diseases. Hemorrhagic cystitis is a major potential toxicity and dose limiting side effect of cyclophosphamide. The aim of this study was to evaluate the effects of lycopene compared with some antioxidants for the prevention of cyclophosphamide induced hemorrhagic cystitis in rats. Methods: ...

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ژورنال

عنوان ژورنال: Drugs - Real World Outcomes

سال: 2017

ISSN: 2199-1154,2198-9788

DOI: 10.1007/s40801-017-0112-y